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Naklee M. Brisbane Sickle Cell Memorial Fund is a proud 501c3 tax exempt organization to support our community and we ask for your help to sponsor our work. Please give what you can and feel good about strengthening a cause important to you and the community. If you would like to support us with a contribution, you may donate today using one of the methods below.

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What is Sickle Cell?

Sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell disease have red blood cells that contain mostly hemoglobin S, an abnormal type of hemoglobin. Sometimes these red blood cells become sickle-shaped (crescent shaped) and have difficulty passing through small blood vessels. When sickle-shaped cells block small blood vessels, less blood can reach that part of the body. Tissue that does not receive a normal blood flow eventually becomes damaged.

This is what causes the complications of sickle cell disease. There is currently no universal cure for sickle cell disease. Sickle cells are destroyed rapidly in the body of people with the disease causing anemia, jaundice and the formation of gallstones.

The sickle cells also block the flow of blood through vessels resulting in lung tissue damage (acute chest syndrome), pain episodes (arms, legs, chest and abdomen), stroke and priapism (painful prolonged erection). It also causes damage to most organs including the spleen, kidneys and liver.

Damage to the spleen makes sickle cell disease patients, especially young children, easily overwhelmed by certain bacterial infections. (www.sickcelldisease.org)